How the medications are used
Mifepristone blocks a hormone needed for a pregnancy to continue. Misoprostol is taken afterward and causes the uterus to empty through cramping and bleeding. Follow the schedule and route provided by the prescribing clinician rather than instructions from an unverified source.
Medication abortion is not used to treat an ectopic pregnancy. A clinician should review symptoms and risk factors that may require evaluation.
Bleeding, cramping, and other expected effects
Bleeding can be much heavier than a menstrual period, and cramping may be severe. Nausea, vomiting, diarrhea, headache, dizziness, fever, and chills can occur. The amount and timing vary, so use the instructions and contact number supplied by the clinician who prescribed the medication.
Warning signs that need prompt medical care
The FDA medication guide says to contact a health professional promptly for bleeding that soaks through two thick, full-size sanitary pads per hour for two consecutive hours; a fever of 100.4°F or higher lasting more than four hours; or abdominal pain or feeling sick more than 24 hours after misoprostol.
Go to an emergency department if you cannot reach the prescribing clinician or if you have severe pain, fainting, weakness, trouble breathing, or another symptom that feels life-threatening.
Sources:3
Follow-up confirms whether treatment is complete
A follow-up plan may use a phone call, symptoms, laboratory testing, a pregnancy test, ultrasound, or an in-person visit. Contact the prescribing clinician if pregnancy symptoms continue or if you are unsure whether the treatment was complete.
Care Net does not perform or refer for abortions. Care Net is not an emergency service. If you have already taken abortion medication, questions about dosing, complications, or follow-up belong with the prescribing clinician or an emergency department.
Information on this page is general education, not medical or legal advice. Talk with an appropriately licensed professional about your situation.
Sources and review
Where this information comes from
Independent sources support the medical, legal, and community information on this page. Care Net's service details are maintained as current first-party information.
- Questions and answers on mifepristone through ten weeks gestationU.S. Food and Drug Administration · Independent source
- Abortion careAmerican College of Obstetricians and Gynecologists · Independent source
- Mifepristone tablets medication guideU.S. Food and Drug Administration · Independent source
Sources last reviewed .

